6 comments

  • embedding-shape 46 minutes ago
    > The work also benefits from recent research into the use of hallucinogens in treating mental illness, which has promoted broader acceptance of these substances. “There was long a feeling that drugs made you sick and addicted,” says José Capriles, an archaeologist at Pennsylvania State University (Penn State) who excavates in Bolivia. “Today, there is a new openness,” he adds, which is freeing grant money and attracting graduate students.

    I'm really happy to hear things like this. The potential benefits (and drawbacks, of course) been evident to lots of us psychonauts for a long time, and finally the sentiment seems to have turned enough so some money can actually get into the research to see if these things can help us today via treatments. A real joy to see after so many decades of the failed war on drugs that influenced policies across the globe.

  • clickety_clack 1 hour ago
    Given that many of our current-day subterranean environments are also covered in art and strewn with drug paraphernalia, can we really say that it played a key role in the rise of the civilization?
    • gchamonlive 1 hour ago
      All you can really say is that negligence is corrosive to civilization, and maybe that drugs act as an amplifier of sorts for society's illnesses and qualities.
      • boogieknite 30 minutes ago
        could also say a corroded civilization makes vulnerable people feel bad and drugs make them feel good
    • dyauspitr 1 hour ago
      You can 100% say that European civilization was heavily, heavily influenced by the consumption of alcohol.
  • theturtletalks 1 hour ago
    I read many years ago that psychedelics are what lead to the formation of consciousness. And it’s supported by the fact that psychedelics are also a network like the brain is. And when taking them, your brain experiences plasticity and that’s what allows profound changes.

    A big part of our consciousness is the default mode network (which is a default of how we operate day to day, things we think about, etc). Psychedelics allow us to change that DMN, but may it have created it too?

    • talon8635 1 hour ago
      How are psychedelic chemical compounds “a network”? Are you referring specifically to fungal mycelium? Of course there a tons of non psychedelic mushrooms and tons of non-mushroom psychedelics
    • whakim 26 minutes ago
      There are a number of problems with these statements, but a major one is that psychedelics are associated with reduced activity within the DMN (but increased activity between the DMN and other networks). It is not clear the direction in which this causality runs.
    • fugalfervor 46 minutes ago
      There is no evidence of that. What you say is not supporting, but rather "conveniently makes sense".

      I don't dispute the utility of psychedelics. But I have observed (and this is anecdotal) that the fanatic devotees of the drugs tend to engage in magical thinking around the power/history/whatever of psychedelic substances, no matter their intelligence or accomplishment, or rigorous critical thinking in other areas.

      • theturtletalks 40 minutes ago
        It’s a controversial theory, but it does exist[0]. As far as I know, there is no prevailing theory about where consciousness came from so speculating based on existing theories isn’t claiming it’s the truth.

        Is it such a leap that fungi are one of the few natural drugs that cause brain elasticity so maybe our early ancestors took it to get the evolutionary process started.

        0. https://en.wikipedia.org/wiki/Stoned_ape_theory

        • robbiep 31 minutes ago
          One of the reasons this is such a long bow to draw is that, as you have absurdly reiterated and an earlier commenter posited, this is Lamarckism. If it is true, where are all the sapient reindeer and other animals that have consumed these substances as a species for as long or longer than we have existed?
    • plufz 1 hour ago
      Just for clarification. The default mode network is what activates when we are at rest or ”not focused on the outside world”. Ie daydreaming and mind wandering, even if it also can be active during detailed thinking.

      It has also been shown to have negative correlation to networks in the brain associated with attention.

    • anramon 38 minutes ago
      > psychedelics are what lead to the formation of consciousness

      This reads like recycled lamarckism.

      • nephihaha 5 minutes ago
        "This reads like recycled lamarckism."

        Recycled Lamarckianism would be Lysenkoism. :)

    • titanomachy 1 hour ago
      > psychedelics are also a network like the brain is

      Sorry to be rude, but what the hell does that mean?

      • theturtletalks 1 hour ago
        Fungi grow as a vast interconnected network and can communicate to other fungi. Similarly to how the neurons in the brain communicate.

        In fact, when you take fungi, it tones down common neural pathways and allows new ones to form between new places.

        • titanomachy 1 hour ago
          Ok, but there are plenty of psychedelics that don't come from fungi.
          • theturtletalks 55 minutes ago
            True, but my point isn’t that. It’s that fungi operate as an interconnected network so it makes the connection between them, neural networks, and consciousness interesting.
            • boothby 50 minutes ago
              Meth is a crystal, and crystals vibrate in synchronous harmonicity. What does this tell us about meth?

              ... no, the fact that some hallucinogens are derived from fungi does not give rise to consciousness. I accept that you read that somewhere; that does not make it true. But, really bad ideas do seem like amazing epiphanies if you're under the influence!

              • quchen 5 minutes ago
                Or take DMT as a crystalline, naturally produced substance. As far as I know, there's no Methamphetamine in nature, although I've become very careful with the terms none/all in biology.
              • theturtletalks 35 minutes ago
                Nice strawman you got there. Meth is a man made synthetic compound. Fungi cover this earth and are one of the few natural drugs that cause brain elasticity and can cause personality change.

                The theory is real and, of course, controversial[0]. The formation of consciousness is still a mystery and I’m simply discussing a theory. If you have another theory you deem right, let’s argue on merit, not personal attacks.

                0. https://en.wikipedia.org/wiki/Stoned_ape_theory

                • boothby 24 minutes ago
                  A theory can be "real" in the sense that people believe it, and also controversial because it has little consistent evidence behind it.

                  https://en.wikipedia.org/wiki/Flat_Earth

                  Nowhere in my comment did I attack you personally. I made an analogous argument; reductio ad absurdum. LSD is also a man-made synthetic compound, and promotes neuroplacticity. And if you've ever known a meth addict, you'll know that the substance can cause significant and enduring personality change.

                  You're advancing a pseudoscientific theory, and I'm ripping it on its utter lack of merit. Please don't take that personally.

              • LoganDark 39 minutes ago
                > really bad ideas do seem like amazing epiphanies if you're under the influence!

                Sometimes really bad ideas can actually turn around when taken to irrational extremes. Tons of evidence in history of people who are batshit crazy, somehow figuring out something amazing simply by being impossibly committed to something really, really stupid. But of course, being batshit crazy has other problems, and nearly all of the really stupid stuff does not turn around like that.

  • baxtr 1 hour ago
    Didn’t mind-altering drugs like alcohol play a key role in the rise of any civilization?
    • adzm 5 minutes ago
      Alcohol and fermentation have a much different role with food safety and preservation though; the inebriation is just a pleasant side effect for some (and a curse for others)
    • LoganDark 1 hour ago
      Alcohol is a poison, not a drug, but I also think so.

      I honestly wish mind-altering drugs were more accessible sometimes, mostly because of safety. Millions are killed by adulterants in their street drugs.

      • nickff 1 hour ago
        As the saying goes: “the dose makes the poison”. Many (perhaps most) drugs cause harm at the wrong dosage.
        • quchen 31 minutes ago
          Depending on your definition of poison of course, but at least for LSD and magic mushrooms, all that's known is a lower bound for their biological toxicity. For LSD IIRC it's somewhere in the 30mg (!) range, for mushrooms it's more than can comfortably fit a stomach. I'm afraid I don't have sources handy though.

          That said, the state of mind must be so wild that "is it poisonous in this specific/usual sense" is probably not the right thing to discuss.

        • embedding-shape 53 minutes ago
          > Many (perhaps most) drugs cause harm at the wrong dosage.

          Not only drugs, almost everything is bad at the wrong dosage. Case in point: water.

          • LoganDark 50 minutes ago
            Tonicity matters too. Deionized water will suck the ions right out of you. All the way to your death if you're so determined.
      • talon8635 1 hour ago
        Poison is a function of dosage. Water is a poison in a high enough dose.

        What’s you’re arguments it’s not a drug?

        • LoganDark 54 minutes ago
          Alcohol requires an astronomical intake compared to most drugs, and I'd say the indiscriminate action and lack of any particular affinity is what makes it a poison as opposed to a drug. It is also generally assumed that alcohol is not exactly in the same category as drugs. ("drugs or alcohol" etc.)
    • dominotw 1 hour ago
      yes coffee is reason behind our current civilization
      • cyberpunk 1 hour ago
        I can't quit it. When I do, after about 2 weeks I completely lose the ability to be a good worker bee and sit in my open plan office,and hide my contempt for the absolute rank ineptitude of almost everyone else there. Load me up with the happy brown juice and I can pretty much make it through. I'm not convinced this is sustainable tbh.
        • shagie 42 minutes ago
          > ... I completely lose the ability to be a good worker bee ...

          Caffeine in Floral Nectar Enhances a Pollinator's Memory of Reward - https://www.science.org/doi/10.1126/science.1228806

          > Caffeine improves memory in humans, millions of whom find that their daily dose enhances clarity, focus, and alertness. The human relationship with caffeine is relatively recent, however, and thus its impact on our brains is likely a by-product of its true ecological role. Caffeine occurs naturally in the floral nectar of Coffea and Citrus plants. Wright et al. (p. 1202; see the Perspective by Chittka and Peng) found that caffeine presented at naturalistic levels significantly improved the ability of bees to remember and locate a learned floral scent and potentiated the responses of neurons involved in olfactory learning and memory.

          PBS Eons Why Does Caffeine Exist? (5:13 for the bit on bees) - https://www.youtube.com/watch?v=PzshAqowsyI

          > In experiments on bees, researchers have found that once they've had a sip of caffeine-laced nectar, it boosts their memory, makes them preferentially revisit the plants, and even helps them pollinate faster and more efficiently. So, for plants, caffeine is a multi-purpose molecule with a lot of adaptive benefits. But, for us, it has one main benefit: it gets us through Monday morning. ...

        • EMIRELADERO 42 minutes ago
          Chesterton called it, quite fittingly, "The Puritan's opium".
    • physicalecon 1 hour ago
      [dead]
  • DUDE_LSD_LMAO 1 hour ago
    [flagged]
    • LoganDark 52 minutes ago
      Give me enough drugs and I'll create civilization too
  • dyauspitr 1 hour ago
    So if you take a lot of psychedelics you end up with a civilization that ritually murders 20,000 people every couple of months.

    Just imagine the power you could wield as a shaman with drugs like DMT and psilocybin it would look like a literal magic

    • TFNA 1 hour ago
      Are you thinking of the Aztecs or Mayans thousands of kilometers away? Andean human sacrifice involved customs unable to provide that level of throughput.